CoverageForm 410-K10-Q8-K13D13G13F

ALNY · Alnylam Pharmaceuticals, Inc. - Financials

Annual line items from SEC XBRL filings, sourced from EDGAR's Company Facts API with fallback to the quarterly Financial Statement Data Sets. See issuer overview for Form 4 activity and 10-K signals.

Price · ALNY

Income Statement

Line itemQ4 '25Q3 '25Q2 '25Q1 '25Q4 '24Q3 '24Q2 '24Q1 '24Q4 '23Q3 '23
Revenue-$1.25B$773.69M$594.19M-$500.92M$659.83M$494.33M-$264.31M
Cost of Revenue-$197.23M$142.03M$70.18M-$81.98M$67.27M$54.61M-$79.47M
Gross Profit-$1.05B$631.66M$524.01M-$418.94M$592.55M$439.72M-$184.83M
R&D-$358.81M$323.62M$265.12M-$270.93M$294.14M$261.00M-$253.18M
SG&A-$322.08M$323.31M$239.95M-$220.99M$248.40M$210.80M-$199.18M
Total Operating Expenses-$881.04M$789.89M$576.11M-$577.82M$611.21M$537.77M-$536.66M
D&A----------
Operating Income-$367.98M($16.20M)$18.08M-($76.91M)$48.61M($43.44M)-$213.87M
Interest Expense-$44.40M$40.25M$35.25M-$34.38M$30.04M$35.25M-$30.89M
Income Tax-($12.12M)$30.92M$15.88M-$2.91M$5.72M$2.35M-$2.99M
Net Income-$251.08M($66.28M)($57.48M)-($111.57M)($16.89M)($65.94M)-$147.75M
EPS - Basic-$1.91($0.51)($0.44)-($0.87)($0.13)($0.52)-$1.18
EPS - Diluted-$1.84($0.51)($0.44)-($0.87)($0.13)($0.52)-$1.15

Balance Sheet

Line itemQ4 '25Q3 '25Q2 '25Q1 '25Q4 '24Q3 '24Q2 '24Q1 '24Q4 '23Q3 '23
Cash & Equivalents$1.66B$1.49B$1.11B$1.02B$966.43M$1.10B$968.49M$681.88M$812.69M$1.03B
Accounts Receivable$777.57M$964.77M$567.11M$418.04M$405.31M$353.85M$309.48M$321.38M$327.79M$325.44M
Inventory$82.72M$75.38M$71.69M$65.58M$78.51M$75.99M$83.98M$93.99M$89.15M$95.77M
Accounts Payable$115.72M$117.59M$102.39M$97.40M$88.42M$70.81M$73.98M$78.15M$55.52M$73.84M
Current Assets$4.05B$3.95B$3.64B$3.27B$3.30B$3.36B$3.17B$2.99B$2.98B$2.99B
Total Assets$4.97B$4.85B$4.57B$4.21B$4.24B$4.21B$4.01B$3.82B$3.83B$3.84B
Current Liabilities$1.47B$1.56B$1.30B$1.08B$1.19B$1.22B$1.06B$941.71M$967.79M$949.78M
Long-term Debt----------
Total Liabilities$4.18B$4.62B$4.32B$4.10B$4.17B$4.17B$4.01B$4.04B$4.05B$4.00B
Stockholders' Equity$789.18M$233.89M$250.59M$115.44M$67.09M$32.35M($3.07M)($219.27M)($220.64M)($165.87M)
Retained Earnings($6.70B)($7.16B)($7.41B)($7.35B)($7.29B)($7.20B)($7.09B)($7.08B)($7.01B)($6.87B)

Cash Flow

Line itemQ4 '25Q3 '25Q2 '25Q1 '25Q4 '24Q3 '24Q2 '24Q1 '24Q4 '23Q3 '23
Operating Cash Flow---($118.31M)---($81.52M)--
Investing Cash Flow---$113.77M---($67.62M)--
Financing Cash Flow---$44.08M---$28.91M--
CapEx---$8.97M---$12.97M--
Free Cash Flow---($127.28M)---($94.49M)--

Ratios

MetricQ4 '25Q3 '25Q2 '25Q1 '25Q4 '24Q3 '24Q2 '24Q1 '24Q4 '23Q3 '23
Profitability
Gross margin-84.2%81.6%88.2%-83.6%89.8%89.0%-69.9%
Operating margin-29.5%-2.1%3.0%--15.4%7.4%-8.8%-80.9%
EBITDA margin----------
Net margin-20.1%-8.6%-9.7%--22.3%-2.6%-13.3%-55.9%
Free cash flow margin----21.4%----19.1%--
FCF / Net income---2.21---1.43--
R&D / Revenue-28.7%41.8%44.6%-54.1%44.6%52.8%-95.8%
SG&A / Revenue-25.8%41.8%40.4%-44.1%37.6%42.6%-75.4%
Effective tax rate--5.1%-------2.0%
Return on assets-5.2%-1.5%-1.4%--2.7%-0.4%-1.7%-3.8%
Return on equity-107.3%-26.4%-49.8%--344.8%550.7%30.1%--89.1%
Return on invested capital----------
Liquidity
Current ratio2.762.542.803.042.782.753.013.173.083.14
Quick ratio2.712.492.752.982.712.692.933.072.993.04
Cash ratio1.130.960.860.950.810.900.920.720.841.09
Leverage
Debt / Equity----------
Debt / Assets----------
Debt / EBITDA----------
Interest coverage-8.3x-0.4x0.5x--2.2x1.6x-1.2x-6.9x
Equity multiplier6.2920.7418.2236.5063.20129.97-1307.35-17.44-17.36-23.15
Liabilities / Assets0.840.950.950.970.980.991.001.061.061.04
Efficiency
Asset turnover-0.260.170.14-0.120.160.13-0.07
Inventory turnover-2.621.981.07-1.080.800.58-0.83
Days sales outstanding-282d268d257d-258d171d237d-449d
Days inventory outstanding-140d184d341d-338d456d628d-440d
Days payable outstanding-218d263d507d-315d401d522d-339d
Cash conversion cycle-204d189d91d-281d225d343d-550d
Valuation
P / E-247.8x-------154.0x
P / B-267.8x170.0x303.3x-1093.1x----
P / S-50.1x55.1x58.9x-70.6x46.7x38.1x-88.0x
EV / EBITDA----------
Growth
Revenue growth (YoY)-149.3%17.3%20.2%-89.5%107.0%131.8%-0.0%
Revenue CAGR (3y)-67.8%51.0%40.7%-38.7%44.1%40.7%-28.1%
Revenue CAGR (5y)-58.2%49.4%43.0%-48.2%71.3%71.5%-72.9%
Gross profit growth (YoY)-151.1%6.6%19.2%-126.7%143.4%155.9%--18.9%
Operating income growth (YoY)-------71.0%--
Net income growth (YoY)---292.4%12.8%--93.9%62.1%--
EPS growth (YoY)---292.3%15.4%--94.1%62.9%--
EPS CAGR (3y)----------
EPS CAGR (5y)----------
FCF growth (YoY)----34.7%---47.6%--
FCF CAGR (5y)----------
Book value growth (YoY)1076.3%622.9%----99.2%15.4%-39.5%-145.2%

Sales by segment

From XBRL dimensional facts in the 10-K period ending 2025-12-31.

Product / service

$9.58B total
Product$2.99B · 31.2%
TTR$2.49B · 26.0%
Amvuttra$1.73B · 18.1%
Collaborations$553.37M · 5.8%
Rare$499.92M · 5.2%
License Obligation$300.00M · 3.1%
License$300.00M · 3.1%
GIVLAARI$205.72M · 2.1%
Royalty$174.02M · 1.8%
Development Services Obligation$89.00M · 0.9%
OXLUMO$68.47M · 0.7%
ONPATTRO$62.13M · 0.6%
Other License Programs$50.37M · 0.5%
Research Services Obligation$39.52M · 0.4%
C5 License Obligation$21.64M · 0.2%
Product And Service Other$5.88M · 0.1%
Regeneron Technology Transfer Obligation$2.43M · 0.0%

Peer comparison

Same SIC group: Pharmaceutical Preparations

CompanyRevenue (last FY)Net marginROE
LLY$65.18B31.7%77.8%
UTHR$3.18B41.9%18.8%
PFE$62.58B12.4%9.0%
ZTS$9.47B28.2%80.2%
VRTX$12.00B32.9%21.2%

Comparing ALNYLAM PHARMACEUTICALS against the 5 most active filers in the same SIC group.