CoverageForm 410-K10-Q8-K13D13G13F

Leaderboard

Insiders and issuers ranked by realized signed return on open-market Form 4 trades. Returns are signed: a sale followed by a rally counts against the seller.

What the metrics mean

Return - the insider's signed return per trade, averaged. A +10% stock move on a buy scores +10%; on a sell, -10%. Because most insider activity is concentrated at rallying stocks, this metric correlates with raw stock performance and doesn't fully isolate timing skill from market drift.

Edge - signed return minus the stock's average forward N-day return over the same period. An insider with +5% edge consistently chose better days to trade than someone who'd picked a random day in the same window. Isolates timing skill from "the stock just went up."

Neither metric is the same as ranking stocks by raw return - that would just surface the best-performing tickers, which you can get from any market screener.

Insiders ranked

298

Showing 50 of 298

Quality filters

10+ trades

≥3 issuers, 50% price coverage

Window

5y trailing

Trade date filter

#InsiderTradesIssuersWin rateAvgMedianBestWorst
1Topper James N18/21672%+70.5%+27.9%+227.4%-22.3%
2Flagship Pioneering Inc.11/133100%+57.3%+9.4%+192.9%+4.7%
3Afeyan Noubar14/194100%+47.0%+9.4%+192.9%+4.7%
4Tananbaum James B.11/19464%+37.2%+43.7%+89.8%-28.3%
5Foresite Capital Fund V, L.P.12/19558%+34.1%+43.7%+89.8%-28.3%
6Foresite Capital Management V, LLC12/19558%+34.1%+43.7%+89.8%-28.3%
7Foresite Capital Opportunity Fund V, L.P.12/19558%+34.1%+43.7%+89.8%-28.3%
8Foresite Capital Opportunity Management V, LLC12/19558%+34.1%+43.7%+89.8%-28.3%
9Wilks Matthew30/31370%+22.2%+11.1%+98.4%-15.2%
10Corre Partners Management, LLC58/70359%+19.5%+8.5%+106.1%-9.2%
11Breber Pierre R23391%+19.4%+23.7%+23.7%-6.4%
12Chernett Jorey31/36374%+18.7%+12.5%+85.9%-24.7%
13Demichele Michael37365%+18.6%+3.1%+256.2%-11.4%
14Mfn Partners Gp, LLC37365%+18.6%+3.1%+256.2%-11.4%
15Mfn Partners Management, LLC37365%+18.6%+3.1%+256.2%-11.4%
16Mfn Partners Management, LP37365%+18.6%+3.1%+256.2%-11.4%
17Mfn Partners, LP37365%+18.6%+3.1%+256.2%-11.4%
18Nanji Farhad37365%+18.6%+3.1%+256.2%-11.4%
19Leone Douglas M25396%+18.1%+15.9%+36.5%-19.7%
20Column Group Opportunity III Gp, LP31/41477%+16.2%+8.3%+78.3%-6.6%
21Column Group Opportunity III, LP31/41477%+16.2%+8.3%+78.3%-6.6%
22Tcg Opportunity III Gp, LLC31/41477%+16.2%+8.3%+78.3%-6.6%
23Radoff Family Foundation10/14380%+15.7%+13.5%+48.6%-2.0%
24Forager Fund, L.P.30487%+15.6%+15.0%+55.0%-6.5%
25Kissel Edward Urban30487%+15.6%+15.0%+55.0%-6.5%
26MacArthur Robert Symmes30487%+15.6%+15.0%+55.0%-6.5%
27Botha Roelof31/35694%+15.4%+12.9%+36.5%-25.3%
28Sylebra Capital LLC13/18392%+15.3%+12.5%+44.3%-15.8%
29Enright Patrick G14/16786%+14.8%+15.6%+38.1%-3.1%
30Rodgers Thurman J25/314100%+14.2%+9.5%+55.6%+0.8%
31Strobeck Matthew17/24471%+13.7%+5.0%+36.4%-25.1%
32Martin William C23370%+13.3%+11.9%+54.1%-10.5%
33Koh Bong Y37/53384%+12.8%+11.2%+35.5%-12.1%
34Vhcp Co-Investment Holdings III, LLC37/53384%+12.8%+11.2%+35.5%-12.1%
35Vhcp Management Eg, LLC37/53384%+12.8%+11.2%+35.5%-12.1%
36Vhcp Management III, LLC37/53384%+12.8%+11.2%+35.5%-12.1%
37Venrock Healthcare Capital Partners Eg, L.P.37/53384%+12.8%+11.2%+35.5%-12.1%
38Venrock Healthcare Capital Partners III, L.P.37/53384%+12.8%+11.2%+35.5%-12.1%
39Heyer Andrew R22/23355%+12.7%+12.9%+49.0%-19.1%
40Shah Nimish P38/54484%+12.6%+11.1%+35.5%-12.1%
41Baker Bros. Advisors LP380/4121385%+12.0%+12.3%+94.7%-85.2%
42Baker Felix380/4121385%+12.0%+12.3%+94.7%-85.2%
43Baker Julian380/4121385%+12.0%+12.3%+94.7%-85.2%
44Baker Bros. Advisors (Gp) LLC380/4121385%+12.0%+12.3%+94.7%-85.2%
45Fairmount Funds Management LLC14/20679%+11.4%+6.2%+55.7%-14.5%
46McBirney Collin41668%+11.4%+6.8%+58.4%-17.6%
47Topline Capital Management, LLC41668%+11.4%+6.8%+58.4%-17.6%
48Topline Capital Partners, LP41668%+11.4%+6.8%+58.4%-17.6%
49Biotechnology Value Fund II LP59/90759%+11.0%+7.1%+76.1%-29.1%
50Biotechnology Value Fund L P59/90759%+11.0%+7.1%+76.1%-29.1%

Showing 1-50 of 298

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Trades are signed. Filters exclude single-issuer leaders to guard against single-stock luck.