MLSS Milestone Scientific Inc. - 8-K

Item
1.01 — Entry into a Material Definitive Agreement

On
March 31, 2026, Milestone Scientific Inc. (the “Company”) entered into an amendment (the “Amendment”) to the
Amended and Restated Memorandum of Understanding, dated January 13, 2026 (the “MOU”), with Innovest S.p.A., as the holder
of certain consent/blockage rights with respect to BP4 S.r.l., a society’ a responsibility’ limitation in liquidation (“BP4”).
According to BP4, it was then the owner of 11.31% of the outstanding shares of common stock of the Company

The
Amendment amends the MOU to, among other things, revise the definition of “Qualified Offering” and “Other Locked-Up
Parties” in order to facilitate an offering by the Company.

A
copy of the Amendment is attached hereto as Exhibit 10.1 and is incorporated herein by reference.

The
foregoing description of the material terms of the MOU does not purport to be complete and is qualified in its entirety by reference
to such an exhibit.

Item
9.01 — Financial Statements and Exhibits

(d)
Exhibits.

Exhibit
No.

Description

10.1

Amendment to Amended and Restated Memorandum of Understanding, by and between Innovest S.p.A. and Milestone Scientific Inc., dated March 31, 2026.

104

Cover
Page Interactive Data File (embedded within the Inline XBRL document)