Karyopharm Therapeutics Inc.
KPTICIK 0001503802 · Every Form 4 filed by insiders at this issuer. See financials →
Annual report (10-K)
Latest 10-K filed Feb 13, 2026. Sentiment + YoY language diff vs prior year. Read sections →
Signal:NeutralFull-doc fallback
Full filing:tone -0.0100Δ+0.000391% similar+688/-594 ¶
Sentiment via Loughran-McDonald lexicon · YoY diff via Jaccard similarity + paragraph set difference.
Recent 8-K announcements
Per-item disclosure feed. Item 2.02 is the earnings release.
Top insiders
Most active reporters at Karyopharm Therapeutics Inc.
| Name | Roles | Filings |
|---|---|---|
| Mason Michael | Officer | 14 |
| Abate Kristin | Officer | 11 |
| Pakianathan Deepika | Director | 8 |
| Bohlin Garen G | Director | 6 |
| Greene Barry E | Director | 5 |
Top performers
Insiders ranked by realized 90-day signed return on their open-market trades at Karyopharm Therapeutics Inc.. Minimum 3 scored trades. Returns are signed - a sale followed by a rally counts against the insider.
| # | Insider | Trades | Win rate | Avg | Median | Best | Worst |
|---|---|---|---|---|---|---|---|
| 1 | Frenkel Ran | 3 | 100% | +48.3% | +50.7% | +55.0% | +39.2% |
| 2 | Kauffman Michael | 6 | 100% | +48.3% | +50.7% | +55.0% | +39.2% |
| 3 | Shacham Sharon | 6 | 100% | +48.3% | +50.7% | +55.0% | +39.2% |
| 4 | Rangwala Reshma | 9 | 89% | +26.9% | +20.0% | +57.9% | -7.2% |
| 5 | Mason Michael | 15 | 93% | +26.5% | +27.0% | +50.7% | -13.6% |
| 6 | Pakianathan Deepika | 18 | 100% | +19.6% | +21.9% | +27.6% | +2.4% |
| 7 | Poulton Stuart | 15 | 87% | +19.0% | +20.0% | +55.5% | -55.4% |
| 8 | Paulson Richard A. | 38 | 76% | +17.3% | +25.0% | +67.5% | -55.8% |
| 9 | Mano Michael | 8 | 75% | +15.9% | +18.5% | +43.4% | -13.6% |
| 10 | Cheng Sohanya Roshan | 11 | 64% | +14.4% | +17.1% | +50.0% | -13.6% |
All filings
187 Form 4 / 4-A filings, newest first
| Filed | Top transaction | Shares | Price | Value | ||
|---|---|---|---|---|---|---|