ADGM Adagio Medical Holdings, Inc. - 8-K

Item 8.01 Other Events

On May 21, 2026, Adagio Medical Holdings, Inc.
issued a press release entitled “Adagio Medical Submits Premarket Approval Application to FDA for vCLAS® Ventricular Ablation
System for the Treatment of Ventricular Tachycardia.” The full text of the press release is attached hereto as Exhibit 99.1 to this
Current Report on Form 8-K and incorporated herein by reference.

Item 9.01. Financial Statements and Exhibits.

(d) Exhibits.

Exhibit No.

Description

99.1

Press Release, dated May 21, 2026

104

Cover Page Interactive Data File (embedded within the Inline XBRL document)

2