Aptinyx Inc.

APTXCIK 0001674365 · Every Form 4 filed by insiders at this issuer. See financials →

Annual report (10-K)

Latest 10-K/A filed Apr 28, 2023. Sentiment + YoY language diff vs prior year. Read sections →

Signal:NeutralFull-doc fallback

Full filing:tone -0.0013

Sentiment via Loughran-McDonald lexicon · YoY diff via Jaccard similarity + paragraph set difference.

YoY shift: Unscored

Year-over-year tone shift - average net-tone change across Risk Factors and MD&A vs the prior 10-K.

Why YoY instead of absolute: the LM lexicon has ~6.6× more negative words than positive (legal/risk-disclosure language is heavy on hedging), so every 10-K reads bearish on raw tone. Year-over-year change strips that bias and surfaces the actual shift in management's framing.

Per-snippet highlights

Sentence-level sentiment highlighting with category and subcategory filters is coming once the snippet-scoring pipeline lands. For now, dig into the actual section text on the Sections tab.

Top insiders

Most active reporters at Aptinyx Inc.

Name	Roles	Filings
Khanna Ashish	Officer	2
Miller Joan W.	Director	2
Enright Patrick G	Director	1
Gosebruch Henry O	Director	1
Gould Terry P	Director	1

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All filings

13 Form 4 / 4-A filings, newest first

Filed	Insider	Top transaction	Shares	Price	Value
Jan 5, 2023	Kidd Andrew PRESIDENT AND CEO · Director	Holdings only	-	-	-
Jan 5, 2023	Riedel Norbert G EXECUTIVE CHAIRMAN OF THE BOD · Director	Holdings only	-	-	-
Jan 5, 2023	Khanna Ashish CFO AND CBO	Holdings only	-	-	-
May 31, 2022	Koppel Adam Director · 10% Owner	Holdings only	-	-	-
May 31, 2022	Enright Patrick G Director	Holdings only	-	-	-

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